Volume 2, Issue 4 , Pages 173-180, August 2010
Outcomes of Pharmacy Interventions on Pediatric Medication Prescribing Patterns in Taiwan
Article Outline
Background/Purpose
The aim of this study was to assess the long-term effect of pharmacy interventions on patients and health care providers, and switching from prescribing extemporaneous powder dosage forms to liquid dosage forms.
Methods
An education program for parents was conducted. An attitude, knowledge and behavior questionnaire was employed to measure the efficacy of the education program. Medication management policies were then executed by providing an in-service to pediatricians, establishing dosage-switching guidelines and adding liquid dosage forms of necessary medications into the hospital formulary. Dosage-switching guidelines of pediatric medications were established by surveying the most prescribed extemporaneous powder dosage forms at the Taipei Medical University–Wan Fang Hospital. These guidelines were introduced to every pediatrician, nurse and pharmacist. The prescribing rate of extemporaneous powder prescriptions was monitored to measure the outcomes of the interventions.
Results
The mean scores of attitude, knowledge and practice significantly improved towards a positive use of commercially available liquid medications after the patient education program for the parents. Prescriptions for extemporaneous powder dosage forms significantly decreased from 1600 (2.54%) to 13 (0.022%) monthly in the 4th year and were reduced to zero in the 6th year.
Conclusion
This study demonstrated that the pharmacists' interventions were able to change the parents' knowledge, attitude and practice towards pediatric drug dosage forms and the prescribing pattern. Effective assurance in children's medication safety can be achieved through collaboration between medical professionals and parents.
Key Words: dosage switching guidelines , intervention , medication safety , pediatrics
No full text is available. To read the body of this article, please view the PDF online.
References
- . An update on the therapeutic orphan . Pediatrics . 1999;104:585–590
- . Lack of pediatric drug formulations . Pediatrics . 1999;104:607–609
- . Drug research and children . FDA Consum . 2003;37:12–17
- . Stability considerations in liquid dosage forms extemporaneously prepared from commercially available products . J Pharm Pharm Sci . 2006;9:398–426
-
Taiwan Health Reform Foundation. Safety in Pediatric Drug Therapy-The Reasons for THRF to Advocate It. Taipei: Taiwan Health Reform Foundation, 2006. Available at http://www.thrf.org.tw/Uploads/{976B276E-FFA4-4F2A-A53F-D9C011214947}_961118
-.pdf [In Chinese] [Date accessed: December 18, 2007]
- . Breaking the Eight Myths of Pediatric Extemporaneous Powder Drugs . Taipei: Taiwan Health Reform Foundation; 2007; Available at http://www.thrf.org.tw/Uploads/%7B976B276E-FFA4-4F2A-A53F-D9C011214947%7D_961118%E6%96%B0%E8%81%9E%E7%A8%BF%E4%B8%80%E9%99%84%E4%BB%B6.pdf [In Chinese] [Date accessed: December 18, 2007]
- . Pediatrician and compounding pharmacist: a dangerous liaison . Arch Pediatr Adolesc Med . 1996;150:224–226
- . Content uniformity of captopril, furosemide, nadolol and propranolol hydrochloride powder packets extemporaneously compounded from tablets . Chin Pharm J . 2000;52:59–68
- . Neonatal and Pediatric Pharmacology: Therapeutic Principles in Practice . 3rd ed.. Philadelphia: Lippincott Williams and Wilkins; 2005;
- . Clinical pharmacokinetics and pharmacodynamics . In: DiPiro JT , Talbert RL , Wells BG , Yee GC , Matzke G , Posey LM editor. Pharmacotherapy: A Pathophysiologic Approach . 6th ed.. New York: McGraw-Hill Publishing; 2005;p. 33–54
- In: Helms RA , Quan DJ editor. Textbook of Therapeutics: Drug and Disease Management . 8th ed.. Philadelphia: Lippincott Williams and Wilkins; 2006;
- . Pharmacists' attitudes toward diabetes . J Am Pharm Assoc (Wash) . 2000;40:371–377
- . The short-term impact of a continuing medical education program on providers' attitudes toward treating diabetes . Diabetes Care . 1999;22:1929–1932
- Prioritizing strategies for preventing medication errors and adverse drug events in pediatric inpatients . Pediatrics . 2003;111:722–729
- . Study on Quality Assurance of Compounding Process for Pediatric Divided Powders . Taipei: School of Pharmacy, National Taiwan University; 2001;
- . Pharmaceutical perspective of drug therapy in pediatrics . Formos J Med . 2000;4:200–214
PII: S1878-3317(10)60027-7
doi:10.1016/S1878-3317(10)60027-7
© 2010 Taiwan Medical University. Published by Elsevier Inc. All rights reserved.
Volume 2, Issue 4 , Pages 173-180, August 2010
